"Cantargia’s decision to increase the level of ambition in the CAN04 project is among the most important and the most intensified in the company's history. This marks a major step to enhance the value of the CAN04 project and take greater advantage of the potential around the target IL1RAP (Interleukin 1 Receptor Associated Protein).

Cantargia utvecklar antikroppsbaserade läkemedel mot interleukin-1 receptor accessory protein (IL1RAP). Antikroppen CAN04 binder IL1RAP

Thereby, the first patient has formally completed the safety evaluation period according to the clinical protocol. Two additional patients have received therapy with CAN04. About Cantargia Cantargia AB (publ), reg. no. 556791-6019, is a biotechnology company that develops antibody-based treatments for life-threatening diseases. The basis for this is the protein IL1RAP that is involved in a number of diseases and where Cantargia has established a platform.

Cantargia can04

Ytterligare två patienter har påbörjat behandlingen. Inga allvarliga biverkningar har dokumenterats. Utvecklingen av antikroppen CAN04 fortskrider, och data som Cantargia nyligen kommunicerade indikerar en synergistisk effekt med cellgifter. Dessa interimdata är från en en pågående fas IIa klinisk studie. Överföringen av GMP-produktionen till Patheon Biologics B.V ingår i bolagets långsiktiga strategi.

Därmed har den första patienten formellt genomgått säkerhetsutvärderingen i enlighet med det kliniska protokollet. Ytterligare två patienter har påbörjat behandlingen.

Cantargia develops antibody-based pharmaceuticals against IL1RAP. The antibody CAN04 binds IL1RAP with high affinity and functions through both Antibody-Dependent Cellular Cytotoxicity (ADCC) and blockade of IL-1 signaling. Preclinical data show that CAN04 increases the efficacy of chemotherapy.

2021-04-06 · Ultimately, we believe CAN04 is differentiated and Novartis's results should add to the data that will help Cantargia define CAN04's positioning. We value Cantargia at SEK6.86bn or SEK68.5/share. Cantargia genomför för närvarande en fas 1/2a-studie med sin läkemedelskandidat Can04 vid behandling av dels bukspottkörtelcancer och lungcancer. Övergripande resultat väntas kunna utläsas under fjärde kvartalet för indikationen inom bukspottkörtelcancer och i det första kvartalet 2021 inom lungcancer.

10 mar 2021 Cantargia. Novartis bakslag kan inte jämföras med Cantargias Can04, är 'tydligt differentierad' från Novartis kandidat - Edison (Finwire). 2021-03-

The antibody CAN04 binds IL1RAP with high affinity and its anti-tumor activity Cantargia is now in the process of broadening the development activities and the next step is a phase Ib trial investigating CAN04 in combination with the PD1 binding antibody pembrolizumab Cantargia develops antibody-based pharmaceuticals against interleukin-1 receptor accessory protein (IL1RAP).

Thereby, the first patient has formally completed the safety evaluation period according to the clinical protocol.
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The antibody CAN04 binds IL1RAP with high affinity and functions through both blockade Cantargia AB today announced that the IND application regarding the antibody CAN04 has been approved by the US FDA. CAN04, an antibody targeting interleukin 1 receptor accessory protein (IL1RAP), is currently being investigated for treatment of non-small cell lung cancer (NSCLC) and pancreatic cancer (PDAC) in phase IIa clinical development. Cantargia develops antibody-based pharmaceuticals against interleukin-1 receptor accessory protein (IL1RAP).

Cantargia To Present New Data From Preclinical Studies With CAN04 In Non-Small Cell Lung Cantargia. CANTA. NASDAQ Stockholm.
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Utvecklingen av antikroppen CAN04 fortskrider, och data som Cantargia nyligen kommunicerade indikerar en synergistisk effekt med cellgifter. Dessa interimdata är från en en pågående fas IIa klinisk studie. Överföringen av GMP-produktionen till Patheon Biologics B.V ingår i bolagets långsiktiga strategi.

Ytterligare två patienter har påbörjat behandlingen. Inga allvarliga biverkningar har dokumenterats.

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8 Apr 2020 Cantargia develops antibody-based pharmaceuticals against the interleukin 1 receptor accessory protein (IL1RAP). The antibody CAN04 binds

It is developing two antibodies against IL1RAP, nidanilimab (CAN04) and CANxx. Nidanilimab is being studied in a Phase I/II CANFOUR in solid tumours focusing on NSCLC and pancreatic cancer. Exchange, Cantargia ansöker om start av ny klinisk studie kring antikroppen CAN04 och BULL CANTARGIA X2 AVA 1. 0.00. BULL CANTARGIA X3 AVA 1. Nidanilimab (CAN 04) is a humanised monoclonal antibody lacking fucose, being 10 Mar 2021 Cantargia files a clinical trial application with the regulatory Kempen & Co acted as Joint Bookrunner in Cantargia's SEK 564 million Capital Increase The main project, the antibody CAN04, is being studied clinically as 8 Apr 2020 Cantargia develops antibody-based pharmaceuticals against the interleukin 1 receptor accessory protein (IL1RAP).

10 mar 2021 Cantargia AB meddelade idag att en ansökan lämnats in kring en klinisk studie som undersöker antikroppen CAN04 i kombination med

Cantargia: Stärkta i vår uppfattning om CAN04. Interimsdata som Vi adderar 7,3 kronor/aktie för den stora potentialen för CAN04 i kombination med Keytruda och summerar värdet av Cantargias olika projekt… Vi adderar 7,3 Cantargia has formally applied to start a phase I/IIa clinical trial with its proprietary antibody CAN04, directed towards the molecular target IL1RAP This is "Fördelar med CAN04" by Cantargia on Vimeo, the home for high quality videos and the people who Cantargia develops antibody-based pharmaceuticals against interleukin-1 receptor accessory protein (IL1RAP).

Cantargia är ett läkemedelsbolag. AB: Cantargia ansöker om start av ny klinisk studie kring antikroppen CAN04 och FOLFIRINOX i CAN04 - Cancer.